Submitted by 2022018 on Tue, 02/14/2023 - 10:22
Dr. Mohamed Aly Saad Aly, P.Eng.
Position
Assistant Professor
Office Room Number
Office: 419, Phone: +86 (755) 36881002 Ext. 341
Professional
Electrical and Computer Engineering
Email
malysaadaly@gtsi.edu.cn
Personal Website
https://ece.gatech.edu/directory/mohamed-aly-saad-aly
https://scholar.google.com/citations?user=Z3thMSYAAAAJ&hl=en
https://www.researchgate.net/profile/Mohamed-Aly-Saad-Aly
https://www.linkedin.com/in/mohamed-aly-saad-aly-ph-d-p-eng-04284140/
https://orcid.org/0000-0003-0091-2467
https://www.credential.net/d20eb9d3-2e3c-4777-8b70-4fa4eed5324e
Overview

Dr. Aly Saad Aly joined the Department of Electrical and Computer Engineering (ECE) at Georgia Institute of Technology as an Adjunct Assistant Professor in 2022. He also serves as an Assistant Professor in ECE department at the Georgia Tech campus in Shenzhen, Georgia Tech Shenzhen Institute (GTSI). He received his B.Sc. and M.Sc. degrees in Electrical Engineering from the University of South Florida (USF) in 2005 and 2006, respectively. He earned a Ph.D. in Systems Design Engineering from the University of Waterloo (UW) in 2016. His Ph.D. work focused on microfabrication, microfluidics, and lab-on-chip (LOC) for biomedical applications such as on-chip bacterial cell lysis and DNA isolation.

Dr. Aly Saad Aly joined the Department of Biomedical Engineering at Tulane University during his postdoctoral fellowship. During his work at Tulane University, he collaborated with a team of researchers to design and fabricate a portable platform used in neurophysiological studies. He then joined the Department of Electrical Engineering at Miami College of Henan University. Before joining GTSI, Dr. Aly Saad Aly was a Research Professor at Daegu Gyeongbuk Institute of Science & Technology (DGIST). During his work at DGIST, Dr. Aly Saad Aly worked on research related to cell isolation and purification, hydrogel-based immunocytochemistry platforms, and electroceutical approaches for enhancing neural cell myelination and treatment for sarcopenia. Dr. Aly Saad Aly worked in an industrial environment where he was involved in several projects focused on microelectrode arrays (MEAs): design, simulation, and fabrication; diagnostic and real-time image-guided surgery x-ray bio-imaging systems (such as the C or U arm); design, simulation, and testing of portable electrochemical biosensors integrated into optical imaging systems. Dr. Aly holds a Professional Engineer (P.Eng.) Ontario license. 

Dr. Aly Saad Aly’s research interests focus on microfluidics-based LOCs for biomedical applications. Furthermore, his research interests include nanotechnology-based electrochemical biosensors. Moreover, nanoparticles-based smart drug delivery systems for viral and cancer therapy are one of his recent research interests. Additionally, research work based on smart biomaterials such as responsive polymer sand hydrogel is an active research interest for Dr. Aly Saad Aly.

Education
  • University of Waterloo, UW, Ph.D., Systems Design Engineering, June 2016
  • University of South Florida, USF, M.Sc., Electrical Engineering (MEMs and Nanotechnology), December 2007
  • University of South Florida, USF, B.Sc., Electrical Engineering, December 2006
Research Interests
  • Microfluidics-based LOC toward developing low cost and easy-to-use microfluidic devices with ultra-low-power consumption for point-of-care, early detection, diagnosis, analysis, and testing in the healthcare sector.
  • Nanocarrier-based smart drug delivery systems for antiviral and anticancer therapies.
  • 2D-biomaterials interaction with vital biomolecules for biosensor-related applications and devices.
  • Smart biomaterials, such as responsive polymers and hydrogels.
  • Flexible electronics toward wearable physical sensing platforms for healthcare and biomedical applications.
Distinctions & Awards
  • Faculty of Engineering Graduate Scholarship: (UW) (Spring 2013 and Fall 2013)
  • University of Waterloo Graduate Scholarship: (UW) (Spring 2013 and Fall 2013)
  • Ontario Graduate Scholarships in Science and Technology: (UW) (Spring 2010, Winter 2011)
  • Queen Elisabeth II-Graduate Scholarship in Science and Technology: (UW) (Winter 2013)
  • Ryerson Graduate Award (RGA): (Ryerson University)
  • Graduate Teaching Assistants/Associates Scholarship: (USF) (2007)
Publications & Patent

Patents:

  1. Mohamed Aly Saad Aly, Clayton B. Ford, Xin Kai Yang, Michael James Moore, “Integrated microelectrodes and methods for producing thesame,” PCT/US2018/027386, 2018, https://patents.google.com/patent/WO2018191556A9/un 

Journals:

  1. Rehab Ali Ibrahim, Mohamed Aly Saad Aly, Yasmine S. Moemen, Ibrahim El Tantawy El Sayed, Mohamed Abd Elaziz, Hassan Ahmed Khalil “Boosting Sinh Cosh Optimizer and Arithmetic Optimization Algorithm for Improved Prediction of Biological Activities for Indoloquinoline Derivatives,” Chemosphere, Vol. 353:142362, P.P. 1–12, 2024, https://doi.org/10.1016/j.chemosphere.2024.142362

  2. Md Romzan Ali, Md Sakib Hassan, Dipto Debnath Ridoy, Prity Lata Mozumder, Md Sadek Bacchu, Shilpi Das, Md Eashanul Karim Moon, Tamanna Jerin Anannya, Tamim Hasan, Mohamed Aly Saad Aly, Selina Akter, Md Zaved Hossain Khan "Synthesis of novel anti-biofilm agent TiO2@ GO for reducing the formation of Streptococcus mitis biofilm on teeth," 12 April 2024, PREPRINT (Version 1) available at Research Square [https://doi.org/10.21203/rs.3.rs-4121405/v1]
  3. Sudhakarachari Atapakala, Siva Sankar Sana, Balaji Kuppam, Rajender S. Varma, Mohamed Aly Saad Aly, Seong-Cheol Kim, Ramakrishna Vadde “Honey mediated synthesis of zinc oxide nanoparticles, and evaluation of antimicrobial, antibiofilm activities against multidrug resistant clinical bacterial isolates,” Journal of Industrial and Engineering Chemistry, Vol. 135, P.P. 110–121, 2024, https://doi.org/10.1016/j.jiec.2024.01.023
  4. M. I. Hossain, M. A. Khaleque, M. R. Ali, M. S. Hossain, S. M. F. Shahed, M. Aly Sad Aly, Md. Z. H. Khan “Development of electrochemical sensors for quick detection of environmental (soil and water) NPK ions,” RSC Advances, Vol. 14, No. 13, P.P. 9137–9158, 2024, https://doi.org/10.1039/D4RA00034J (https://doi.org/10.1039/D4RA90036G)
  5. Mohamed Morsy, Islam Gomaa, Abd Elhamid M. Abd Elhamid, Heba Shawkey, Mohamed Aly Saad Aly, Amir Elzwawy “Ternary nanocomposite comprising MnO2, GQDs, and PANI as a potential structure for humidity sensing application” Scientific Reports, Vol. 13, No. 21742, P.P. 1–15, 2023, https://doi.org/10.1038/s41598-023-48928-2 
  6. Md. Rashid Al-Mamun, Md. Shahinoor Islam, Md. Romzan Alia, Md. Ikram Hossaina, Mohamed Aly Saad Aly, Md. Zaved Hossain Khan “State-of-the-art in solar water heating (SWH) systems for sustainable solar energy utilization: A comprehensive review,” Solar Energy, Vol. 264: 111998, P.P. 1–27, 2023, https://doi.org/10.1016/j.solener.2023.111998
  7. M. A. Khaleque, M. R. Ali, M. S. Bacchu, M. R. A. Mamun, M. I. Hossain, M. S. Hossain, Mohamed Aly Saad Aly, M. Z. H. Khan “Zinc oxide Nanorod/Rutin Modified Electrode for the Detection of Thiourea in Real Samples,” Heliyon, Vol. 9, No. 10, P.P. 1–25, 2023, https://doi.org/10.1016/j.heliyon.2023.e20676         
  8. S. Saha, M.R. Ali, M. A. Khaleque, M. S. Bacchu, M. Aly Saad Aly, Md. Zaved H Khan “Metal oxide nanocarrier for targeted drug delivery towards the treatment of global infectious diseases,” Journal of Drug Delivery Science and Technology, Vol. 86: 104728, P.P. 1–14, 2023, https://doi.org/10.1016/j.jddst.2023.104728 
  9. M. A. Khaleque, M. I. Hossain, M. R. Ali, M. S. Bacchu, M. Aly Saad Aly, M. Z. H. Khan “Nanostructured wearable electrochemical and biosensor towards healthcare Management: A review,” RSC Advances, Vol. 13, No. 33, P.P. 22973–22997, 2023, https://doi.org/10.1039/D3RA03440B
  10. Tianyu Hou, Siva Sankar Sana, Divya Vishambhar Kumbhakar, Huizhen Li, Vijaya Kumar Naidu Boya, Mohamed Aly Saad Aly, Zhijun Zhang, Tien Duc Pham “Synthesis of sodium-alginate capped silver nanocomposite microgel beads via bio-reduction featuring multifunctional antibacterial and apoptotic properties in human prostate cancer,” Journal of Drug Delivery Science and Technology, Vol. 87, No. 104799, P.P. 1–17, 2023, https://doi.org/10.1016/j.jddst.2023.104799
  11. Md. Shamim Hossain, Md. Abdul Khaleque, Md. Romzan Ali, Md. Sadek Bacchu, Md. Ikram. Hossain, Mohammed Aly Saad Aly, Md. Zaved Hossain Khan “Poly(3,4-ethylenedioxythiophene):Polystyrene Sulfonate-Modified Electrode for the Detection of Furosemide in Pharmaceutical Products,” ACS Omega , Vol. 8, No. 19, P.P. 16851–16858, 2023, https://doi.org/10.1021/acsomega.3c00463
  12. Yaser Alaiwi, Azher M. Abed, Ghassan Fadhil Smaisim, Mohamed Aly Saad Aly, Salema K. Hadrawi, Reza Morovati “Simulation and investigation of bioethanol production considering energetic and economic considerations,” International Journal of Low-Carbon Technologies, Vol. 18, P.P. 191–203, 2023, https://doi.org/10.1093/ijlct/ctad008
  13. M. R. Ali, M. S. Bacchu, S. Das, S. Akter, M. M. Rahman, M. Aly Saad Aly, M. Z. H. Khan “Label free flexible electrochemical DNA biosensor for selective detection of Shigella flexneri in real food samples,Talanta, Vol. 253, No. 1, P.P. 123909–123919, 2023, https://doi.org/10.1016/j.talanta.2022.123909
  14. Jannatul Naime, Muhammad Shamim Al Mamun, Mohamed Aly Saad Aly, Md. Maniruzzaman, Md Mizanur Rahman Badal, Kaykobad Md Rezaul Karim “Synthesis, characterization and application of a novel polyazo dye as a universal acid-base indicator,” RSC Advances, Vol. 12, No. 43, P.P. 8034–28042, 2022, https://doi.org/10.1039/D2RA04930A 
  15. M. R. Hasan, M. Daizy, M. R. Ali, M. Aly Saad Aly, M. Z. H. Khan, M. S. Hossain “Recent Advancements in MXene Research Towards Biosensor Development,” Critical Reviews in Analytical Chemistry, P.P. 1–18, 2022, https://doi.org/10.1080/10408347.2022.2115286
  16. Aseer Intisar, Woon-Hae Kim, Hyun Young Shin, Min Young Kim, Yu Seon Kim, Heejin Lim, Hyun Gyu Kang, Yun Jeoung Mo, Mohamed Aly Saad Aly, Yun-Il Lee, Minseok S. Kim “An Electroceutical Approach Enhances Myelination via Upregulation of Lipid Biosynthesis in Dorsal Root Ganglion,” Biofabrication, Vol. 14, No. 1, P.P. 1–13, 2022, https://doi.org/10.1088/1758-5090/ac457c
  17. M. H. Rahman, M. N. Hasan, S. Nigar, F. Ma, M. Aly Saad Aly, M. Z. H. Khan “ZnO hollow spheres arrayed molecular-imprinted polymer based sensitive electrochemical sensor for methyl-parathion pesticide detection,” Environmental Technology & Innovation, Vol. 24: 101847, P.P. 1–9, 2021, https://doi.org/10.1016/j.eti.2021.101847
  18. Md. Hafizur Rahman, Md. Nazmul Hasan, Shireen Nigar, Fanya Ma, Mohamed Aly Saad Aly, Md. Zaved Hossain Khan “Synthesis and Characterization of a Mixed Nanofertilizer Influencing the Nutrient Use Efficiency, Productivity, and Nutritive Value of Tomato Fruits,” ACS Omega, Vol. 6, No. 41, P.P.  27112–27120, 2021, https://doi.org/10.1021/acsomega.1c03727
  19. M. R. Hasan, M. S. Ahommed, M. Daizy, M. S. Bacchu, M. R. Ali, M. R. Al-Mamun, M. Aly Saad Aly, M. Z. H. Khan, M. S. Hossain “Recent Development in Electrochemical Biosensors for Cancer Biomarkers Detection,” Biosensor and Bioelectronics: X, Vol. 8: 100075, P.P. 100075–100086, 2021, https://doi.org/10.1016/j.biosx.2021.100075
  20. M. R. Ali, M. S. Bacchu, M. R. Al-Mamun, M. M. Rahman, M. S. Ahommed, M. Aly Saad Aly, M. Z. H. Khan “Sensitive MWCNT/P-Cys@MIP sensor for selective electrochemical detection of Ceftizoxime,” Journal of Materials Science (JMSC), Vol. 56, No. 22, P.P. 12803–12813, 2021, https://doi.org/10.1007/s10853-021-06115-6 
  21. Mahbuba Daizy, Chaitaly Tarafder, Md. Rashid Al-Mamun, Liu Xiuhua, Mohamed Aly Saad Aly, Md. Zaved Khan “Electrochemical Detection of Melamine by Using Modified GCE/P-Arg/ ErGO-CuNFs Electrode,” ACS Omega, Vol. 4, No. 23, P.P. 20324–20329, 2019, https://doi.org/10.1021/acsomega.9b02827   
  22. P. Velusamy, Shiya Chen, Shanhu Liu, R. Ramesh Babu, Mohamed Aly Saad Aly, E. Elangovan, Haibo Chang, Ruimin Xing “Investigating the effect of Nd3+ dopant and the formation of g-C3N4/BiOI heterostructure on the microstructural, optical and photoelectrocatalytic properties of g-C3N4” Applied Surface Science, Vol. 561: 150082, P.P. 150082–150095, 2021, https://doi.org/10.1016/j.apsusc.2021.150082
  23. M. R. Ali, M. S. Bacchu, M. R. Al-Mamun, M. S. Ahommed, M. Aly Saad Aly, M. H. Khan “N-Hydroxysuccinimide crosslinked graphene oxide-gold nanoflower modified SPE electrode for sensitive detection of Chloramphenicol antibiotic,” RSC Advances, Vol. 11, No. 26, P.P. 15565–15572, 2021, https://doi.org/10.1039/D1RA02450G
  24. Sanjeev Dalawai, Mohamed Aly Saad Aly, Ashok Gadkari, Pranod N. Vasambekar “Investigating the Influence of Titanium ion Substituted Cd-Al-Mn Ferrite Composites on The Structural, DC Resistivity and Electrical Switching,” To Chemistry Journal, Vol. 7, P.P. 106-123, ISSN: 2581-7507, 2020.
  25. Chaitaly Tarafder, Mahbuba Daizy, Md. Morshed Alam, Md. Ripon Ali, Md. Jahidul Islam, Rakibul Islam, Md. Sohel Ahommed, Mohamed Aly Saad Aly, and Md. Zaved Hossain Khan “Formulation of a Hybrid Nanofertilizer for Slow and Sustainable Release of Micronutrients” ACS Omega, Vol. 5, No. 37, P.P. 23960–23966, 2020, https://doi.org/10.1021/acsomega.0c03233
  26. Sanjeev Dalawai, Mohamed Aly Saad Aly, Sanjay Latthe, Xing Ruimnin, Rajaram Sutar, Saravanan Nagappan, Chang-Sik Ha, Kishor Sadasivuni and Shanhu Liu “Recent Advances in Durability of Self-Cleaning Technology: a Critical Review” Progress in organic coatings, Vol. 138: 105381, PP. 1–15, 2020, https://doi.org/10.1016/j.porgcoat.2019.105381  
  27. Quazi Salma Siddiqua, Chaitaly Tarafder, Mahbuba Daizy, Md. Sohel Ahommed, Md. Riaju Islam, Nazmen Nahar, Md. Rafiu Hasan, Md. Rashid Al-Mamun, Mohamed Aly Saad Aly, Md. Zaved Hossain Khan “Application of Stabilized Cefixime-AgNPs-GO Thin Films as Corrosion Inhibitors for Mild Steel Alloy,” To Chemistry Journal, Vol. 3, P.P. 15–24, ISSN: 2581-7507, 2019.
  28. Sanjeev P. Dalawaia, Surender Kumar, Mohamed Aly Saad Aly, Md. Zaved H. Khan, Ruimin Xing, Pramod N. Vasambekar, Shanhu Liu “A review of spinel-type of ferrite thick film technology: fabrication and application,” Journal of Materials Science: Materials in Electronics (JMSE), Vol. 30, No. 8, P.P. 7752–7779, 2019, https://doi.org/10.1007/s10854-019-01092-8 
  29. Mohamed Aly Saad Aly, Mario Gauthier, John T. W. Yeow “On-Chip Cell Lysis by Antibacterial Non-leaching Reusable Quaternary Ammonium Monolithic Column” Biomedical Microdevices, Vol. 406, No. 1, P.P. 1–13, 2016, https://doi.org/10.1007/s10544-015-0025-z
  30. Mohamed Aly Saad Aly, Mario Gauthier, John T. W. Yeow “Lysis of Gram-positive and Gram-negative Bacteria by Antibacterial Porous Polymeric Monolith Formed in Microfluidic Biochips for Sample Preparation,” Analytical and Bioanalytical Chemistry, Vol. 406, No. 24, P.P. 5977–5987, 2014, https://doi.org/10.1007/s00216-014-8028-9
  31. Mohamed Aly Saad Aly, Olivier Nguon, Mario Gauthier, John T. W. Yeow “Antibacterial Porous Polymeric Monolith Columns with Amphiphilic and Polycationic Character on Cross-linked PMMA Substrates for Cell Lysis Applications,” RSC Advances, Vol. 3, No. 46, P.P. 24177–24184, 2013,  https://doi.org/10.1039/C3RA43087A 

Conferences:

  1. Hyun Gyu Kang, Aseer Intisar, Hanwoong Woo, Yun-I Lee, Mohamed Aly Saad Aly, Minseok S. Kim “Promyelinating Effect of Electrical Stimulation on PMP22 Overexpressed Schwannoma Cells” The 19th Proceeding of International Nanotech Symposium & Exhibition (NANO KOREA 2021), P.P. 7–9 July 2021, Kintex, Korea.
  2. Mohamed Aly Saad Aly, Nibardo Lopez, Daniel Weyers, Sarbast Rasheed, Eihab Abd Alrhman, Arsen Hajian “Investigating Carbon Nanotubes for MRI Receiver Coils” Proceedings of the ISMRM Annual Meeting Montreal, 6–13 May 2011, https://cds.ismrm.org/protected/11MProceedings/files/3884.pdf
  3. Manu Pallapa, Mohamed Aly Saad Aly, Albert I.H. Chen, Lawrence Wong, Ka Wai Wong, Eihab Abdel-Rahman John Tze-Wei Yeow “Modeling and Simulation of a Piezoelectric Micro-power Generator,” Proceedings of COMSOL Users Conference. PP (1-7). 7-9 Oct. 2010, Boston, MA USA. ISB: 978-0-9825697-4-0, https://www.comsol.dk/paper/download/62841/pallapa_paper.pdf
  4. Mohamed Aly Saad Aly and Jing Wang “Design and Simulation of Mechanically-Coupled Filters Based on ZnO Piezoelectrically Transduced Contour Mode Ring Resonators,” Proceeding of International Conference On Nanotechnology: Fundamentals and Applications (ICNFA2010). P.P. 5041–5048, 4-6 Aug. 2010, Ottawa, Canada.